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mitoxantrone-loaded stearic acid/Pluronic F68/DOTAP nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

1

octadecanoic acid

stearic acid SA
Type Single Compound
Formula C18H36O2
Role core
2

1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione

1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino) ethylamino]-anthracene-9,10-dione mitoxantrone mitox MTO MTX Mit
Type Single Compound
Formula C22H28N4O6
Role loaded material
3

poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer

Pluronic F68
Type Polymer
Formula
Role layer
4

N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium

(N-[1-(2, 3-dioleoyloxy)propyl]-N,N,N-trimethylammoniumsalt) 1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane 1,2-dioleoyloxy-3-trimethylammonium-propane 1,2-dioleoyl-3-(trimethylammonium)propane 1,2-dioleoyl-3-trimethyl-ammonium-propane 1,2-dioleoyl-3-trimethylammonium propane 1,2-dioleoyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammonium-propan 1,2-dioleoyl-3-trimethylammoniumpropane DOTAP
Type Single Compound
Formula C42H80NO4
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Characterization

Biological effects

Biological system Test details Source
human mammary cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione
  • water
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
See all (6)
  1. OBSfRBwXq
  2. trrKUp
Product

mitoxantrone-loaded stearic acid/Pluronic F68/DOTAP nanoparticles

References

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