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gemcitabine-loaded PLGA-PEG-NH2 nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

1

PLGA-PEG-NH2 diblock copolymer

Type Polymer
Formula
Role carriers
2

(4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-1,2-dihydropyrimidin-2-one)

2',2'-difluoro-2'-deoxycytidine 2',2'-difluorodeoxycytidine gemcitabine gemzar dFdC GEM Gem
Type Single Compound
Formula C9H11F2N3O4
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug entrapment efficiency

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
scanning electron microscopy

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Biological effects

Biological system Test details Source
human pancreatic carcinoma MIA PaCa-2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-1,2-dihydropyrimidin-2-one)
  • PLGA-PEG-NH2 diblock copolymer
  1. CaNhHEFEz0iJqA
  2. 0t8
  3. 1I3Vm
  4. ZyYYD4M1ai
Product

gemcitabine-loaded PLGA-PEG-NH2 nanoparticles

References

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