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paclitaxel-loaded polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate block copolymer nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role carriers
2

polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate copolymer

PLA-TPGS
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast adenocarcinoma MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

paclitaxel-loaded polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate block copolymer nanoparticles

Hydrodynamic diameter: 122.2 - 129.2 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate copolymer
  • Paclitaxel
  1. xKF7x4r
  2. EUWhaCrfjD
Product

paclitaxel-loaded polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate block copolymer nanoparticles

Hydrodynamic diameter: 122.2 - 129.2 nm

Medium/Support: none

References

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