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paclitaxel-loaded PEG-PCL nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene glycol)-co-poly(ε-caprolactone)

PEG-PCL
Type Polymer
Formula
Role core
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

maleimide residue

maleimide moiety maleimide group maleimide
Type Single Compound
Formula -C4H2NO2
Role layer
4

methoxy terminus

methoxy moiety methoxy group methoxy
Type Single Compound
Formula CH3O-
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
brain capillary endothelial cell

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • methoxyl poly(ethylene glycol)-co-poly(ε-caprolactone)
  • maleimide-poly(ethylene glycol)-co-poly(ε-caprolactone)
  • Paclitaxel
  1. 62Fh1E7Kh9UC07sPjuQz54XYo
  2. bndRq4eFgGiYPXy7BUzMnLkB5wcKE
  3. 80Wbx
Product

paclitaxel-loaded PEG-PCL nanoparticles

References

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