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self-assembled gene delivery system XM001-BikDD

Based on

1 Articles
2014 Most recent source

Composition

1

BikDD solution

Type Complex Compound
Formula
Role core
2

N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium

(N-[1-(2, 3-dioleoyloxy)propyl]-N,N,N-trimethylammoniumsalt) 1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane 1,2-dioleoyloxy-3-trimethylammonium-propane 1,2-dioleoyl-3-(trimethylammonium)propane 1,2-dioleoyl-3-trimethyl-ammonium-propane 1,2-dioleoyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammonium propane 1,2-dioleoyl-3-trimethylammonium-propan 1,2-dioleoyl-3-trimethylammoniumpropane DOTAP
Type Single Compound
Formula C42H80NO4
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role layer
4

N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium

(N-[1-(2, 3-dioleoyloxy)propyl]-N,N,N-trimethylammoniumsalt) 1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane 1,2-dioleoyloxy-3-trimethylammonium-propane 1,2-dioleoyl-3-(trimethylammonium)propane 1,2-dioleoyl-3-trimethyl-ammonium-propane 1,2-dioleoyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammonium propane 1,2-dioleoyl-3-trimethylammonium-propan 1,2-dioleoyl-3-trimethylammoniumpropane DOTAP
Type Single Compound
Formula C42H80NO4
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mice bearing MDA-MB-231-Luc tumors

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • cholesterol
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
  1. qCrDGfujcJ
  2. vAYs
  3. b3PvAD
Product

self-assembled gene delivery system XM001-BikDD

Diameter: 238.7 - 261.3 nm

Medium/Support: none

References

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