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methoxy polyethylene glycol-b-polycaprolactone/paclitaxel-poly(lactide) conjugate/cisplatin-poly(lactide) conjugate nanoparticles

Based on

1 Patents
2013 Most recent source

Composition

1

methoxy polyethylene glycol-b-polycaprolactone

Type Polymer
Formula
Role raw materials
2

carboxylic acid-terminated polylactide-paclitaxel conjugate

carboxylic acid-terminated PLA-paclitaxel conjugate
Type Polymer
Formula
Role raw materials
3

polylactide-cisplatin conjugate

PLA-cisplatin conjugate
Type Polymer
Formula
Role raw materials

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polylactide-cisplatin conjugate
  • carboxylic acid-terminated polylactide-paclitaxel conjugate
  • tetramethylene oxide
Product

methoxy polyethylene glycol-b-polycaprolactone/paclitaxel-poly(lactide) conjugate/cisplatin-poly(lactide) conjugate nanoparticles

Size: not specified

Medium: water/tetrahydrofuran mixture

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • polylactide-cisplatin conjugate
  • carboxylic acid-terminated polylactide-paclitaxel conjugate
  • tetramethylene oxide
Product

methoxy polyethylene glycol-b-polycaprolactone/paclitaxel-poly(lactide) conjugate/cisplatin-poly(lactide) conjugate nanoparticles

Size: not specified

Medium: water/tetrahydrofuran mixture

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • polylactide-cisplatin conjugate
  • carboxylic acid-terminated polylactide-paclitaxel conjugate
  • tetramethylene oxide
Product

methoxy polyethylene glycol-b-polycaprolactone/paclitaxel-poly(lactide) conjugate/cisplatin-poly(lactide) conjugate nanoparticles

Size: not specified

Medium: water/tetrahydrofuran mixture

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • polylactide-cisplatin conjugate
  • carboxylic acid-terminated polylactide-paclitaxel conjugate
  • tetramethylene oxide
Product

methoxy polyethylene glycol-b-polycaprolactone/paclitaxel-poly(lactide) conjugate/cisplatin-poly(lactide) conjugate nanoparticles

Size: not specified

Medium: water/tetrahydrofuran mixture

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • polylactide-cisplatin conjugate
  • carboxylic acid-terminated polylactide-paclitaxel conjugate
  • tetramethylene oxide
Product

methoxy polyethylene glycol-b-polycaprolactone/paclitaxel-poly(lactide) conjugate/cisplatin-poly(lactide) conjugate nanoparticles

Size: not specified

Medium: water/tetrahydrofuran mixture

Support: none

References

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