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paclitaxel-loaded DHA-PLys(S-S)P micelles

Based on

1 Articles
2014 Most recent source

Composition

1

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role core
2

polypeptide copolymer

CH3O-PEG-pLys-pPhe MPEG-pLys-pPhe
Type Polymer
Formula
Role layer
3

dehydroascorbic acid-conjugated CH3O-PEG-pLys-pPhe

DHA-pLys-pPhe
Type Polymer
Formula
Role layer
4

sodium 3,3'-dithiobis(sulfosuccinimidylpropionate)

3,3'-dithiobis(sulfosuccinimidylpropionate) DTSSP
Type Single Compound
Formula C14H14N2Na2O14S4
Role other

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
Balb-c nude mouse bearing glioma

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • dehydroascorbic acid-conjugated CH3O-PEG-pLys-pPhe
  • polypeptide copolymer
  • N,N'-dimethylformamide
See all (4)
Product

paclitaxel-loaded DHA-PLys(S-S)P micelles

Hydrodynamic diameter: 44 - 50 nm

Medium: N,N'-dimethylformamide

Support: none

References

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