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Her2-PLI/XIAP-siRNA polyplexes

Based on

1 Articles
2014 Most recent source

Composition

1

copolymer of poly(ethylene glycol) and poly-(L-lysine) grafting polyethylenimine

mPEG45-b-PLL42-g-(ss-lPEI15)10 mPEGn-b-PLLm-g-(ss-lPEIp)q mPEG-b-PLL-g-(ss-lPEI) PLI
Type Polymer
Formula
Role raw materials
2

Herceptin-functionalized PEG

Her2-PEG-COOH
Type Complex Compound
Formula
Role graft
3

ribonucleic acid

XIAP siRNA siRNA
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
nude mouse BALB/c bearing subcutaneous xenografts of Skov-3 tumor

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • Herceptin-functionalized PEG
  1. pxHvHAew
  2. cwTIC3SICO9g5Cb6vmVd9jEMmpO4FJLlDPaRK9Ncgm3MPqxr43Pem70g8l38qqpDbL4iSZqmqaTdCOtvNniYo1dpdBjlyzGQHW
Product

Her2-PLI/XIAP-siRNA polyplexes

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • Herceptin-functionalized PEG
  1. mx8shrUI
  2. Zzotfak8FwiqeNO7GjtQGh1wv7Ei9UvKOoDYfjNmLGSMVznQWMTTBdjfmqb6L1SUk4zgHpZT3JsflzDo2G7cNOVVkdMhXZD6FK
Product

Her2-PLI/XIAP-siRNA polyplexes

References

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