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siRNA-loaded HA/CS-g-PEG nanoparticles

Based on

1 Articles
2010 Most recent source

Composition

1

mixture of substance based on (pentasodium tripolyphosphate anhydrous/poly(ethylene glycol)-grafted chitosan/hyaluronic acid)

Type Complex Compound
Formula
Role carriers
2

EGFP-specific siRNA duplex

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
HEK-293 cells stably expressing EGFP protein

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • hyaluronic acid
  • poly(ethylene glycol)-grafted chitosan
  • EGFP-specific siRNA duplex
See all (4)
  1. Nbhr4gg3UrXYos
Product

siRNA-loaded HA/CS-g-PEG nanoparticles

Size: 140.3 - 161.3 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • hyaluronic acid
  • poly(ethylene glycol)-grafted chitosan
  • EGFP-specific siRNA duplex
See all (4)
  1. yvGG4EygiKMEUi
Product

siRNA-loaded HA/CS-g-PEG nanoparticles

Size: 228.2 - 272.8 nm

Medium/Support: none

References

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