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docetaxel-loaded 0% crosslinkable lipid shell nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role core
3

soybean lecithin

Type Complex Compound
Formula
Role layer
4

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-carboxy(polyethylene glycol)2000

DSPE-PEG2000-COOH
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
H460 (human lung cancer) cell

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-carboxy(polyethylene glycol)2000
  • poly(lactic-co-glycolic acid)
  • soybean lecithin
Product

docetaxel-loaded 0% crosslinkable lipid shell nanoparticles

References

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