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polyethylenimine fullerene encapsulated with folic acid conjugated with docetaxel

Based on

1 Articles
2013 Most recent source

Composition

1

(C60-Ih)[5,6]fullerene

buckminsterfullerene C60 fullerene fullerene-C60 [60]fullerene buckyball C60 C60
Type Single Compound
Formula C60
Role raw materials
2

poly(iminoethylene)

polyethyleneimine polyaziridine PEI
Type Polymer
Formula
Role graft
3

folic acid

FA
Type Single Compound
Formula C19H19N7O6
Role layer
4

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
release profile of docetaxel dependent on time

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
female BALB/c mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. 9JV0SZQfvUApWEE1C0
  2. k5ZnRPHrJz
Product

polyethylenimine fullerene encapsulated with folic acid conjugated with docetaxel

Size: 137.3 - 142.7 nm

Medium: water

Support: none

References

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