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RGD-attached methotrexate-loaded poly(DL-lactic-co-glycolic acid) gold half-shell nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(DL-lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role raw materials
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role raw materials
3

poly(ethylene glycol)

PEG
Type Polymer
Formula
Role graft
4

RGD-attached gold half-shell

Type Nano Material
Formula
Role graft

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
vis-NIR absorbance

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
DBA/1J mouse with rheumatoid arthritis

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. MUHB23rh4
  2. AvS7KtsbFoNx
Product

RGD-attached methotrexate-loaded poly(DL-lactic-co-glycolic acid) gold half-shell nanoparticles

Diameter: 115 nm

Medium/Support: none

References

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